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Scleromalacia Perforans


Updated June 18, 2014

Written or reviewed by a board-certified physician. See About.com's Medical Review Board.

Definition: Scleromalacia perforans is a serious eye condition that can result in loss of vision. Scleromalacia perforans, also known as necrotizing scleritis, is the most severe form of scleritis, sometimes leading to loss of the eye. The condition is often associated with systemic disease and involvement of multiple organs.

Scleromalacia perforans is characterized by severe thinning of the sclera of the eye, and can be categorized into two types, with inflammation and without inflammation. This type of scleritis is often associated with severe rheumatoid arthritis.

Also Known As: Necrotizing scleritis
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